Frequently Asked Questions


Does the Oxygen MKV Series require a power supply?

No, the Oxygen MKV Series is a low-power device and can be fully powered via USB. Simply connect the included USB cable to an available port on your computer to power the unit and trigger software synths!

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Do I need to install any drivers to use my Oxygen MKV Series controller?

The M-Audio Oxygen MKV series is a class-compliant device, meaning that it is plug-and-play and does not require any drivers to be installed.

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What operating systems is the Oxygen MKV Series compatible with?

Since the Oxygen MKV Series is class-compliant, it will operate off of your computer's core MIDI drivers providing compatibility for the most recent macOS and Windows operating systems.

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What are the system requirements for the included software?

Ableton Live Lite:

  • Mac:
    • OS X 10.11.6 or later
    • Intel® Core™2 Duo Processor (Intel® Core™ i5 processor or faster recommended)
    • 4 GB RAM (8GB or more recommended)
  • PC:
    • Windows 7 (SP1), Windows 8, or Windows 10 (64-bit)
    • 64-bit Intel® Core™ or AMD multi-core processor (Intel® Core™ processor or faster recommended)
    • 4 GB RAM (8GB or more recommended)

MPC Beats:

  • Mac:
    • OS X 10.13.0 or later
    • Intel® i5 processor
    • 4GB RAM (8GB or more recommended)
  • PC:
    • Windows 10
    • Intel® i5 processor
    • 4GB RAM (8GB or more recommended)

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What software comes with the Oxygen MKV Series?

The Oxygen MKV Series comes with the following software:

  • DAWs
    • MPC Beats
    • Ableton Live Lite
  • Virtual Instruments
    • Mini Grand 
    • Hybrid 
  • Sound Packs
    • MPC Beats Producer Kits
    • F9 Instruments Beats Edition
    • LANIAKEA Sounds
    • MSX Audio
    • ADSR Lofi

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Which DAWs can I use this controller with?

The Oxygen MKV Series will integrate with any DAW or software platform that accepts MIDI data. Refer to your software's documentation for more information on how to set up an external MIDI device.

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Can I use the Oxygen MKV Series without a computer?

Definitely! If you prefer to work without a computer, the Oxygen MKV can be powered by a USB cable connected to a USB wall adapter and routed to an external sound module via the MIDI DIN output port.

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Where can I access my included software?

We've included  MPC Beats, Ableton Live Lite, MPC Sound Packs, and a library of instrument and effect plugins with your Oxygen Pro so you can get started making music with professional software right out of the box!

All software will be made available in your M-Audio account after registering the unit. To register the Oxygen Pro:

  1. Go to

  2. Hover over the Account tab at the top right and select Sign In.

    Note: If you are a new customer, select Create Account first and fill in the necessary information. When you're ready, click Create Account.

  3. Enter your email address and password. Click Sign In.

  4. Your account dashboard will appear. Click on Register Product.

  5. Select your Oxygen ## MKV model from the Product field's drop-down menu.

  6. Next, enter the Oxygen MKV's serial number exactly as it appears on the bottom of the unit. The serial number will be located on a barcode sticker and starts with a (21). Be sure to include the (21) when entering the serial number!

  7. Enter the date of purchase in the final field.

  8. When you're done, click Register My Product.

  9. Your Oxygen MKV will be added to the My Products page with download links for all of your included software. You can access this page at any time from your main account page. We recommended downloading the Oxygen Pro Series Software Manager first as this will guide you through the installation process for all of your included software

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How do I set up the Oxygen MKV Series in Ableton Live Lite?

  1. First, connect Oxygen MKV to your computer. Then launch Ableton Live Lite.

  2. Open the Ableton Live Lite Preferences window. If you are using a Mac, go to Live > Preferences. If you are using a PC, go to Options > Preferences.

  3. Select the Link / MIDI tab on the left. Under the MIDI Ports section, adjust the settings as follows:
    • Under Control Surfaces, for Input and Output select Oxygen ## DAW (Port 2).
    • Next to Input: Oxygen ##, select On in the Track column (if using the Oxygen ## as the external clock source, turn on Sync).
    • Next to Input: Oxygen ## (Port 2), select On in the Track and Remote columns.
    • Next to Output: Oxygen ##, select On in the Track column (if using the Ableton Live as the external clock source, turn on Sync).
    • Next to Output: Oxygen ## (Port 2), select On in the Track and Remote columns.
  4. Close the Preferences window.

  5. To add an instrument or plugin to trigger with Oxygen ##, select Instruments or Plug-ins in the Categories column.

  6. In the Name column to the right of the Categories column, locate the Instrument or Plug-in of your choice. Click-and-drag the instrument to a MIDI track in Ableton Live Lite to load the instrument.

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How do I set up the Oxygen V Series in MPC Beats?

  1. First, connect the Oxygen MKV Series to your computer with the provided USB cable. Then launch MPC Beats.

  2. Open MPC Beats from your computer's Application or Program folder.

  3. MPC Beats will list a selection of project templates and demos to get you up and running with the software. If you prefer to start with a clean slate click on Empty Project.

  4. If you're new to MPC and would like to find out more about its features and functions, click on the Open Help or Watch Videos buttons at the right!

  5. Let's open the MIDI/Sync Preferences to ensure that the Oxygen is enabled as an active MIDI input device. Navigate to the Preferences menu and click on the MIDI/Synctab.
    • MAC: Select MPCBeats > Preferences
    • PC: Select EDIT > Preferences

  6. The Input Ports section in MIDI/Sync Preferences will display all available MIDI input ports in a list. Devices will automatically appear in the list when connected provided that Enable MIDI ports when discovered is set to ON.

  7. Enable Track for the following Input Ports:
    • Oxygen ##
    • MIDIIN3 (Oxygen ##)

  8. Enable Track for the following Output Ports:
    • Oxygen ##
    • MIDIIN3 (Oxygen ##)

  9. By default, the Oxygen Pro's Input Port will be set to Track. Let's take a look at the different input modes and how they can be used:
    • When Master is enabled, MIDI data from this port will always go to the currently selected program in your project.
    • When Control is enabled, MIDI data from this port will be sent to MIDI Learn.
    • When Track is enabled, this MIDI port will appear in the list of available MIDI Inputs that can be selected in your track's Channel Strip or in Track View.

  10. If you plan on using MPC Beats as an external clock with the Oxygen MKV's Arp or Note Repeat functions, you'll need to enable Sync next to the Oxygen ## Output Port. Additionally, activate Sync Send. Click on the Sync Output field and select MIDI Clock.

  11. You can load an instrument by creating a Plugin Program and clicking the Plugin field. A Browser will appear with your MPC plugins and AIR plugins. Click on a plugin and then click Select. The Instrument can now be triggered with the Oxygen Pro.

    Can't see the plugin GUI? Just click on the Pop-Out icon to the right!

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Will the transport buttons, rotary knobs, and faders control my DAW automatically?

You can set the keyboard to automatically coordinate with your DAW’s features or set it to work as a personally customized controller. In DAW Mode, the keyboard’s controls will be automatically mapped to sliders, buttons, knobs, and pads in your DAW.

To set the keyboard to operate in DAW Mode, press the DAW Button. The button will be lit to show that DAW Mode is selected.

To change which DAW your keyboard is set to control:

  1. Press the DAW Button to activate DAW Mode, which will illuminate the DAW button on your keyboard.

  2. To change what DAW is currently selected, press and hold the SHIFT button and the DAW/PRESET button. The following messages will be shown on the display to indicate which setting has been selected.
    • NC1: Mackie 1: Will send standard Mackie messages. Mackie control is typically used for DAWs like Cubase, Studio One, Logic, and Reaper.
    • NC2: Mackie 2. Will send standard Mackie messages, but with higher resolution for the pan pots. If your DAW's pan isn't able to do a full sweep of the pan pot, use Mackie 2. Mackie control is typically used for DAWs like Cubase, Studio One, Logic, and Reaper.
    • M|h: Mackie/HUI will send standard Mackie/HUI messages for DAWs like Pro Tools.
    • N1: MIDI 1 will send 1 set of standard MIDI messages for use with Ableton.
    • N2: MIDI 2 will send 1 set of standard MIDI messages for use with MPC Beats, and Reason

Refer to our setup guides for additional assistance configuring the Oxygen MKV with your DAW:

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